2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

PDF 2.67 MB

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-125698
    3-Deoxyaphidicolin
    		Inhibitor
    3-Deoxyaphidicolin exhibits phytotoxic efficacy, that inhibits root growth of lettuce seedlings. 3-Deoxyaphidicolin also exhibits leishmanicidal activity against Leishmania major and Leishmania braziliensis.
    3-Deoxyaphidicolin
  • HY-163483
    ELQ-598
    		Inhibitor
    ELQ-598, as a prodrug, is converted into the active drug ELQ-596 upon oral administration. ELQ-598 demonstrates potent parasitic growth inhibition capabilities (IC50= 37 nM). ELQ-598 also shows low toxicity towards human cells (IC50= 19 μM). ELQ-598 can be used for research into babesiosis.
    ELQ-598
  • HY-N8455
    Isocudraniaxanthone A
    		Inhibitor
    Isocudraniaxanthone A is a xanthone that can be isolated from Garcinia vieillardii. Isocudraniaxanthone A has antimalarial activity against chloroquino-resistant strains of Plasmodium falciparum with an IC50 of 2.3 μg/mL.
    Isocudraniaxanthone A
  • HY-B2085
    Arsthinenol
    		Inhibitor
    Arsthinenol (Arsthinol; Balarsen) is an orally active small organic arsenic molecule. Arsthinenol exhibits anti-amoebic activity by eliminating cysts and trophozoites of Entamoeba histolytica in feces and promoting the healing of amoebic rectal ulcers. Arsthinenol forms the hydroxypropyl-β-cyclodextrin inclusion complex STB-HPβCD, which has an IC50 of 31.6 μM against U87 MG cells and possesses anti-tumor activity. Arsthinenol can be used in the research of intestinal amoebiasis and glioblastoma.
    Arsthinenol
  • HY-147856
    Antileishmanial agent-11
    		Inhibitor
    Antileishmanial agent-11 (compound 4d) is a potent anti-leishmanial agent. Antileishmanial agent-11 shows antiprotozoal activity against Leishmania brazilensis, Leishmania infantum, and T. cruzi, with IC50 values of 28.3, 24.8 and 13.0 μM, respectively.
    Antileishmanial agent-11
  • HY-W783593
    Avermectin A1a
    		Inhibitor
    Avermectin A1a is a potent and broad-spectrum antiparasitic agent. Avermectin A1a targets nematodes and arthropods by binding to their glutamate-gated chloride channels to block nerve signal transmission and induce paralysis. Avermectin A1a can be used for the study of parasitic infection.
    Avermectin A1a
  • HY-B1370S
    Hydroxychloroquine-d4 sulfate
    		Inhibitor
    Hydroxychloroquine-d4 (sulfate) is the deuterium labeled Hydroxychloroquine sulfate. Hydroxychloroquine sulfate (HCQ sulfate) is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine sulfate is efficiently inhibits SARS-CoV-2 infection in vitro.
    Hydroxychloroquine-d<sub>4</sub> sulfate
  • HY-120154
    Palitantin
    		Inhibitor
    Palitantin ((±)-Palitantin), a metabolite of Penicillium frequentans on Leishmania brasiliensis, has antiprotozoal effect against Leishmania brasiliensis.
    Palitantin
  • HY-N10743
    Pipercide
    		Inhibitor 99.59%
    Pipercide is an amide of piper nigrum fruits. Pipercide has larvicidal activity to mosquito. Pipercide acts on the nervous system and induces repetitive discharge on the central nerve cord. Pipercide can be used as an insecticide.
    Pipercide
  • HY-156028
    FIKK9.1-IN-1
    		Inhibitor
    FIKK9.1-IN-1 (Compound 1) is a FIKK9.1 inhibitor. FIKK9.1-IN-1 interacts with the ATP?binding residues in FIKK9.1. FIKK9.1-IN-1 is an antimalarial agent (IC50: 2.68 μg/mL) and disrupts the parasite life cycle and leads to the death of parasites.
    FIKK9.1-IN-1
  • HY-147537
    Antileishmanial agent-9
    		Inhibitor
    Antileishmanial agent-9 (compound 16c) has potent and selective activity against Leishmania donovani (L. donovani) with an IC50 value of 4.01 μM. Antileishmanial agent-9 has relatively low cytotoxicity in L-6 cells (IC50 = 40.1 μM).
    Antileishmanial agent-9
  • HY-128430
    Farnesyl acetate
    		Inhibitor
    Farnesyl acetate is a sesquiterpene isolated from the leaves of Amomum gagnepainii. Farnesyl acetate has significant toxicity against red palm weevil larvae with a LD50 of 7867 ppm.
    Farnesyl acetate
  • HY-122385
    Dabequin phosphate
    		Inhibitor
    Dabequin phosphate is an antimalarial agent, that exhibits inhibitory activity against Plasmodium falciparum.
    Dabequin phosphate
  • HY-149938
    Antimalarial agent 25
    		Inhibitor
    Antimalarial agent 25 is an orally active 1,4-naphthoquinones derivative with antimalarial activity. Antimalarial agent 25 shows cytotoxicity against P. falciparum. Antimalarial agent 25 inhibits P. burghei induced parasitemia in vivo.
    Antimalarial agent 25
  • HY-N7082S
    D-Arabinopyranose-13C5
    		Inhibitor 99.9%
    D-Arabinopyranos-13C5 is 13C labeled D-Arabinopyranos (HY-N7082). D-Arabinopyranose is a rare aldehyde pentose, and its ring-opened form is D-arabinose (HY-N0059). D-arabinose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC50 is 7.5 mM). D-arabinose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-arabinose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-arabinose is the ring-opened form of the aldopentose D-?Arabinose (HY-N7082).
    D-Arabinopyranose-<sup>13</sup>C<sub>5</sub>
  • HY-W738270
    Veratraldehyde-13C
    Veratraldehyde-13C (3,4-Dimethoxy[7-13C]-benzaldehyde) is the 13C-labeled Veratraldehyde (HY-N1096). Veratraldehyde is an orally active aromatic compound and antibacterial agent. Veratraldehyde can be isolated from essential oils of plants such as peppermint and ginger. Veratraldehyde targets the PilY1 protein. Veratraldehyde has antibacterial activity against Pseudomonas aeruginosa. Veratraldehyde has a repellent effect against mosquitoes and ticks. Veratraldehyde can be used as a flavoring agent.
    Veratraldehyde-<sup>13</sup>C
  • HY-Y0121R
    Ethyl cinnamate (Standard)
    		Inhibitor
    Ethyl cinnamate (Standard) is the analytical standard of Ethyl cinnamate. This product is intended for research and analytical applications. Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta.
    Ethyl cinnamate (Standard)
  • HY-N16437
    Panowamycin A
    		Inhibitor
    Panowamycin A is an isochroman compound that can be produced by Streptomyces sp. K07-0010. Panowamycin A exhibits antitrypanosomal activity against the Trypanosoma brucei brucei GUTat 3.1 strain (IC50: 0.40 μg/mL). Panowamycin A shows weak cytotoxicity towards human fetal lung fibroblast MRC-5 cells (IC50: 2.95 μg/mL). Panowamycin A can be used for research in the field of antitrypanosomal studies.
    Panowamycin A
  • HY-114969
    Clioxanide
    Clioxanide is a potential anti-liver fluke (Fasciola hepatica) agent. The results showed that Clioxanide showed no efficacy against 4-week-old or 19-week-old flukes at doses of 135 mg/kg or 200 mg/kg. In contrast, hexachloroethane was very effective against older flukes, reaching 100% efficacy at lower doses. The study pointed out that laboratory mice may not be suitable for screening potential compounds against liver fluke infections in ruminants such as cattle and sheep. In addition, no obvious toxic reactions were observed in mice with Clioxanide.
    Clioxanide
  • HY-N18245
    (-)-3-O-Acetylcatechin
    (-)-3-O-Acetylcatechin is a Leishmania amazonensis arginase inhibitor with an IC50 of 3.7 μM. (-)-3-O-Acetylcatechin can be used for the research of leishmaniasis.
    (-)-3-O-Acetylcatechin
Parasite Isoform Comparison

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.